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Neuroblastoma is a common childhood cancer that originates from a part of the nervous system called the autonomic nervous system. This system regulates a person's heart rate, blood pressure and digestion. It usually arises in the nerves of the chest or abdomen and is most common in the adrenal glands located above the kidneys. Neuroblastoma is the third most common childhood cancer and is th...

Plexiform neurofibromas are a type of benign (i.e. nonmalignant, non-spreading) tumor seen in patients most of whom have neurofibromatosis type 1 (for specifics on NF1 please see separate entry). By definition, plexiform neurofibromas are tumors of the peripheral nerve sheath (the insulating material around nerves) that form along large nerve trunks, multiple small branches of nerves, or spinal ro...

Neurofibromatosis type 1 (NF1) is a genetic disorder wherein tumors called neurofibromas grow on the nerves underneath the surface of the skin, thus causing abnormalities noticeable on the skin. NF1 is usually diagnosed in childhood. The effects of the disease vary depending on the extent of the tumor growth, however, most children with NF1 live normal lives. ...

Neurofibromatosis type 2 (NF2) is a genetic disorder that is characterized by the presence of tumors that grow on both sides of the 8th cranial nerve which is responsible for hearing. This condition was once called “bilateral acoustic neurofibromatosis or central neurofibromatosis.” The 8th cranial nerve is named the vestibulocochlear nerve for its two parts, the vestibular and cochlear parts of...

Nezelof Syndrome is a very rare immune disorder where the cells of the body that normally fight against infections do not function properly. This syndrome is also sometimes called combined immunodeficiency (CID) because both of the immune system cells (B cells and T cells) do not work properly. It is different from severe combined immunodeficiency (SCID) (see above), because there is often some fu...

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Full disease list by letter:
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