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Cells, the building blocks of the human body, are home to the genetic information, or blueprints, that determine all of our physical characteristics. These genes are organized into chromosomes, of which there are 23 pairs. Each pair is made up of one chromosome from the mother’s egg and one from the father’s sperm. One of these pairs is very special because it determines the sex of the baby. The sex chromosome can come either in the form of an X or a Y. Girls usually inherit two X chromosomes, one from her mother’s egg and one from her father’s sperm. Boys usually inherit one X chromosome from his mother’s egg, and one Y chromosome from his father’s sperm. XXX Syndrome occurs when the mother’s egg and the father’s sperm combine, and instead of resulting in XX or XY, the baby girl inherits an extra X chromosome (XXX).
Triple X Syndrome
The Triple-X Syndrome site provides information for parents with XXX daughters. The links to the left provide insight into development, biological details, and various articles covering prognosis, psychosocial aspects of the syndrome, and intelligence.
Triple X Support Group
Information about an international Triple X support group.
Contact A Family
An organization providing information and support for families affected by various diseases including Triple X Syndrome. There is a nice description of the syndrome with information about available support.
47,XXX. What is the Prognosis? Mary G. Linden, Bruce Bender, Robert Harmon, David Mrazek, and Arthur Robinson. Pediatrics 82(4). Oct 1988.
Psychosocial Competence of Unselected Young Adults with Sex Chromosome Abnormalities. Bruce Bender, Robert Harmon, Mary Linden, Becki Bucher-bartelson, and Arthur Robinson. American Journal of Medical Genetics. 88: 200-206
1999 Intelligence and Achievement in Children With Extra X Aneuploidy. J. Rovet, C. Netley, J. Bailey, M. Keenan, and D. Stewart. American Journal of Medical Genetics. 60: 356-60. 1995